In his specialist oncology training, Dr De Silva was actively involved in clinical, translational, and laboratory-based research, with a strong focus on cancer genomics and tumour biology. He has contributed to multiple peer-reviewed publications and ongoing research projects across breast, lung, and urological cancers, and his work has been discussed and presented within international academic and clinical settings. This research background underpins his approach to evidence-based, precision cancer care and informs day-to-day clinical decision-making.

During his tenure at Memorial Sloan Kettering Cancer Center (MSKCC), one of the world’s leading cancer research institutions, Dr De Silva was involved in advanced clinical research programs and early-phase therapeutic studies. This included exposure to patients receiving novel targeted and immune-based treatments through clinical trials, in some cases for the first time globally. Working within large metropolitan tertiary hospitals, this experience strengthened his ability to integrate cutting-edge research into personalised cancer treatment strategies, balancing innovation with safety and real- world outcomes.